Coronary Collateral Growth Induced by Physical Exercise

Coronary Collateral Growth Induced by Physical Exercise

Direct demonstration of coronary collateral growth by physical endurance exercise in a healthy marathon runner.

C ardiovascular disease, in particular coronary artery disease (CAD), is the leading cause of death in industrialised countries. Current therapeutic approaches to obstructive CAD include pharmacologic reduction in myocardial oxygen demand or mechanical restoration of blood flow to regions with insufficient blood supply. Alternatively, recent investigations have focused on the growth of vascular...

Coronary collateral function during exercise.

A totally occluded coronary vessel subtending a noninfarcted, entirely collateral-dependent myocardial region (NIECDMR) provides an opportunity to assess collateral perfusion during exercise stress. Collateral function was determined by analysis of exercise thallium-201 myocardial perfusion images from 31 patients who had at least one NIECDMR (total 41 NIECDMRs) documented during catheterizatio...

Coronary collateral growth by external counterpulsation: a randomised controlled trial.

BACKGROUND The efficacy of external counterpulsation (ECP) on coronary collateral growth has not been investigated in a randomised controlled study. Objective To test the hypothesis that ECP augments collateral function during a 1 min coronary balloon occlusion. PATIENTS AND METHODS Twenty patients with chronic stable coronary artery disease were studied. Before and after 30 h of randomly all...

Influence of physical exercise on coronary collateral blood flow in chronic experimental two-vessel occlusion.

In 45 approximately 1-year-old purebred German shepherd dogs, the left circumflex and the right coronary arteries were chronically occluded by implantation of slowly swelling ameroid constrictors. Before the operation, 27 dogs were trained on a treadmill until they could run 8 mph on a 22% incline for 1 hour, 5 days per week. Two weeks after the operation, exercise was gradually resumed and con...